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Incidental Adrenal Mass

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ACR IFC 2017·reviewed 2026-07-01
  • Applies to incidentally detected adrenal masses ≥1 cm in patients ≥18 years old. Masses <1 cm generally require no workup.
  • Consider biochemical evaluation to exclude subclinical hyperfunction (cortisol excess, pheochromocytoma; aldosterone if hypertensive) for indeterminate masses and before any resection or biopsy.
  • Suspicious morphology at any size — heterogeneity, necrosis, irregular margins — should prompt workup regardless of the size branch.

Does the mass have diagnostic benign features?

Unenhanced attenuation ≤10 HU (lipid-rich adenoma), macroscopic fat (myelolipoma), an unequivocal simple cyst, or pure hemorrhage with no underlying enhancing mass.

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Sources

  • Mayo-Smith WW, et al. Management of Incidental Adrenal Masses: A White Paper of the ACR Incidental Findings Committee. J Am Coll Radiol. 2017;14(8):1038-1044.source

Educational reference for clinicians — not medical advice. Verify against the primary source before acting on it; guidelines change. Final decisions rest with the interpreting physician and your institution's protocols.